At the Central Talent Work Conference, important arrangements have been made for building high-caliber talent hubs in Beijing, Shanghai and the Guangdong-Hong Kong-Macao Greater Bay Area, indicated by Xiao Mingzheng, Ying Yan and Zhang Man in an article of the fifth issue of Chinese Public Administrationin 2022. The "high-caliber talent hub" is characterized by the large quantity of talents with high density, the high level of talents, the great vitality of talents, good returns of talent output and good supporting environment for talent development. In this regard, the article proposes a framework for the path --"a hub + three features + three elements + five systems", and a development model with government leading/guidance, strategic planning and market mechanisms; advocates the national strategic direction of overall target positioning, regional characteristics complementation and collaborative innovation. The article also offers suggestions for enhancing internationalization, strengthening the cooperation between industries, universities and research institutes, improving innovation environment and stimulating the vitality of science and technology participants.