Vietnamese scientists plan to producea main material for production of
anti-bird flu medicine Tamiflu from anise, a small tree, in the next few months,
according to local newspaper Young People on Monday.
Vietnam's Chemistry Institute plans, in the next five or six months, to make
Oseltamivir (active agent of Tamiflu) on a laboratory basis out of star anise,
an aromatic Asian evergreen tree having purple-red flowers and star-like
clusters of anise-scented fruit.
The institute's scientists have found out a process of extracting shikimic
acid, a key material to synthesize Oseltamivir, from anise fruit. One hundred
grams of the fruit can turn out 5-10grams of shikimic acid, or six grams of the
fruit can make one Tamiflu capsule.
Vietnam's Health Ministry announced in November 2005 that it had inked a deal
with Roche, Swiss producer of Tamiflu, under which the firm would supply Vietnam
with necessary materials and techniques to manufacture the medicine in the
country. Roche also agreed to supply Vietnam with 25 million Tamiflu capsules in
case of bird flu pandemics.
The northern province of Lang Son with over 8,000 hectares of star anise, the
biggest anise-growing area in Vietnam, annually produces 5,000-6,000 tons of the
dried fruit.
Now, the country uses anise as a spice or extracts oil from it for production
of traditional medicines and export.
Star anise fruit is a star-shaped, dark brown pod that containsa pea-sized
seed in each of its eight segments. It is a commonly used spice and tea
flavoring in Asian cuisines, and widely used toflavor liqueurs and baked goods
in Western cultures.